NOVEL USE OF EBUS-IFB TO DIAGNOSE SOLITARY FIBROUS TUMORS OF THE PLEURA

نویسندگان

چکیده

TOPIC: Procedures TYPE: Fellow Case Reports INTRODUCTION: Endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) is a novel technique that allows higher yield sampling than fine-needle aspiration (FNA) [1]. We present case of the EBUS-IFB utilized to diagnose posterior mediastinal solitary fibrous tumor pleura. CASE PRESENTATION: A 50-year-old male with tobacco dependence and asbestos exposure presented intoxicated complained assault, prompting trauma evaluation. CT chest found an incidental 7.4 cm heterogeneously enhanced mass within right upper hemithorax abutting mediastinum. The patient endorsed chronic back pain, cough, weight loss. Our approach consisted EBUS-FNA 19 gauge needle followed by EBUS-IFB. Immunohistochemistry demonstrated CD34, Vimentin, signal transducer activator transcription 6 (STAT6) protein positive neoplastic cells final diagnosis tumors DISCUSSION: Solitary are rare mesenchymal (SFTP) fibroblastic differentiation characterized NAB2-STAT6 gene fusion on chromosome 12. drives nuclear entry STAT6 protein, facilitating discrimination between histologically similar tumors. does not produce high results for SFTP [2]. In our case, small mini-forceps were passed into targeted following puncture, we obtained adequate tissue make successful diagnosis. To knowledge, this first applied SFTP. CONCLUSIONS: demonstrates use paraspinal This provides less invasive alternative from surgical aid in REFERENCE #1: J Thorac Dis. 2019 Sep;11(9):4049-4058. #2: Curr Opin Pulm Med. 2012 Jul;18(4):339-46 DISCLOSURES: No relevant relationships Kenneth D'Souza, source=Web Response Reiichiro Obata, no disclosure file Muhammad Perwaiz

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ژورنال

عنوان ژورنال: Chest

سال: 2021

ISSN: ['0012-3692', '1931-3543']

DOI: https://doi.org/10.1016/j.chest.2021.07.1747